How does your management of locally advanced NSCLC change in a patient with a previous contralateral pneumonectomy?

I've tried to tackle this a few times in my practice and it's uber hard. Depending on the size, it's often impossible. You are really stuck with the constraints for Mesothelioma in the setting of EPP. That is V20 of 7% and MLD of 8.5 Gy (Int. J. Radiation Oncology Biol. Phys., Vol. 69, No. 2, pp. 35...