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How does your treatment of lymph nodes change for a breast cancer with limited (<2mm) vs more extensive ECE?

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Does the extent of ENE influence your decision to irradiate the dissected axilla after a full axillary dissection?

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2 Answers
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Radiation Oncology · Beth Israel Deaconess Medical Center
Answered on

Extracapsular tumor extension (ENE) alone does not appear to increase the risk of axillary failure following axillary dissection (1, 2). There have been conflicting data on whether ENE increases the risk of local-regional failure (LRF) and whether the degree of ENE is important. Having ENE of 2 mm o...

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Mednet Member
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Radiation Oncology · Varian Medical Systems/Allegheny health network
Answered on

In patients with a dissected axilla, ECE of more than 2 mm would make us treat the undissected axilla (level 3) and supraclavicular region as it is shown to be predictive of regional relapse in retrospective series.

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