How has the ADVISE trial changed your approach to steroid sparing agents for non-infectious uveitis?
In light of the publication from Jabs et al., PMID 41077357.
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What would be your preferred first-line agents for non-infectious uveitis, barring cost and insurance coverage?
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2 Answers
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Rheumatology · Legacy Devers Eye Institute
Answered on · Updated on
The ADVISE trial was a well-designed, multinational trial that compared adalimumab therapy for non-infectious intermediate, posterior, or panuveitis versus conventional immunosuppressive therapy or CID. Two hundred twenty-seven subjects were enrolled over four years, and a fifth year was required to...
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Rheumatology · Baptist Health Jacksonville Rheumatology
Answered on
So I used to work in a uveitis clinic one day per week, and that was an amazing experience. I really do like the idea of doing adalimumab or biologics first line, but the main barrier is insurance coverage. That being said, we still do the dual therapy with DMARD (mtx or mmf) plus TNFi as if the pat...
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