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How long after stopping prednisone do ESR and CRP become clinically reliable for reassessing disease activity?

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After discontinuing prednisone, when do you typically reassess symptoms and interpret ESR/CRP as clinically reliable for disease activity?

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1 Answer
Mednet Member
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Rheumatology · Harvard Medical School
Answered on

As with most issues related to corticosteroids, the dose and duration of use matter. When steroids have been tapered slowly after a lengthy period of use, e.g., patients with PMR, it may take weeks (at the least) until we get a true reading of their ESR and CRP values. For shorter tapers, such as fo...

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