How long do you continue treatment with imatinib in a patient with chronic eosinophilic leukemia who achieves remission?
If indefinite treatment is recommended, is there an optimal maintenance dose?
Answer from: Medical Oncologist at Community Practice
This has not been clearly established. If the patient has the FIP1L1/PDGFR rearrangement, these patients need very low doses for excellent response, typically 100 mg daily. If not, response rates are lower and they usually require higher doses. I would continue therapy indefinitely as TFR has not be...
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