The critical issue with treating serious infections like pyomyositis due to Staph aureus, monomicrobial or polymicrobial necrotizing fasciitis, or Clostridial myonecrosis is assuring adequate surgical debridement. To quote the legendary Dr. Maxwell Finland, when asked on rounds how long to treat a c...
I agree with Dr. @ Winslow, it all depends on the timing and adequacy of the surgery. As for Dr. Finland's comment, I didn't know that one, but I love it.
I have always found it incredible how rarely the Founders of ID were wrong on antibiotic therapy. I put this table together a few years ago from...