How long do you wait before starting a non-selective beta blocker in patients with newly reduced LVEF and recent cocaine use?

Cocaine use is a well-known cause of cardiovascular complications, including acute coronary syndromes, arrhythmias, and cardiomyopathy leading to reduced left ventricular ejection fraction (LVEF). The use of beta-blockers in this context is often debated due to concerns about unopposed alpha-adrenergic stimulation, particularly in acute settings. However, current evidence supports their safe and beneficial use in managing heart failure with reduced ejection fraction (HFrEF) once acute toxicity r...