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How often do you check carnitine levels in your patients with end stage kidney disease on hemodialysis?

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Under what circumstances do you order carnitine levels for an ESKD patient on hemodialysis?

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2 Answers
Mednet MemberInvited Expert
Nephrology · University Of California San Francisco Medical Center At Parnassus
Answered on

About 10 years ago I used to check carnitine levels in ESRD patients with intradialytic hypotension commonly. If low then I would treat with levocarnitine. At some point I gave up on the practice not because it was not working but because it was hard to determine if it was working or not. I am aware that carnitine supplementation has also been used for other associated problems such as ESA resistant anemia. Thanks for this reminder, I will try to check carnitine levels more often again.

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Mednet MemberInvited Expert
Nephrology · Boston University Chobanian & Avedisian School of Medicine
Answered on

I have also checked carnitine only a couple of times over the last few years - once for intradialytic hypotension in a setting of cardiomyopathy on a young patient and another one for ESA-resistant anemia. Cartinine was low in both patients and the supplementation did improve intra-dialytic hypotension but did not remarkably change ESA-resistant anemia. I think there are subsets of patients where this might be helpful.

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