How often do you check carnitine levels in your patients with end stage kidney disease on hemodialysis?
Under what circumstances do you order carnitine levels for an ESKD patient on hemodialysis?
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About 10 years ago I used to check carnitine levels in ESRD patients with intradialytic hypotension commonly. If low then I would treat with levocarnitine. At some point I gave up on the practice not because it was not working but because it was hard to determine if it was working or not. I am aware that carnitine supplementation has also been used for other associated problems such as ESA resistant anemia. Thanks for this reminder, I will try to check carnitine levels more often again.
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I have also checked carnitine only a couple of times over the last few years - once for intradialytic hypotension in a setting of cardiomyopathy on a young patient and another one for ESA-resistant anemia. Cartinine was low in both patients and the supplementation did improve intra-dialytic hypotension but did not remarkably change ESA-resistant anemia. I think there are subsets of patients where this might be helpful.
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