How often do you monitor CD-19 counts and immunoglobulin levels in MS patients on B-cell depletion therapy?

This is a very timely question and one that is largely unresolved. There is currently no consensus on whether or how frequently gamma globulin levels should be monitored. Similarly, there is no consensus regarding the frequency of CD19 monitoring.

Monitoring CD19 counts after rituximab therapy for pa...

The biggest concern is not when/whether you should monitor for CD 19 cell counts but why we don’t. In more ways than one, this question or doubt about the use of anti-CD 20 therapies began in 2017 after the approval of the first drug for multiple sclerosis in this class.

First of all, the frequency ...