How often do you monitor urine protein levels for patients with membranous nephropathy for whom you initiate obinutuzumab?
When do you expect to first see an improvement?
Answer from: at Community Practice
Most studies of obinutuzumab in membranous nephropathy are retrospective, with remission rates of up to 83%. Would monitor UPCR every 1-3 months and check PLA2R every 3 months. Immunological remission (negative PLA2R) precedes clinical remission (one study with 76% at 3 mo and 80% at 6 mo), and clin...