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How significant are the cardiovascular side effects, such as hypertension, associated with valproate?

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Mednet Member
Mednet Member
Neurology · University of Rochester Medical Center

I do not routinely think of cardiovascular side effects, especially HTN, as being a major factor with valproate. I think of things like cardiac conduction changes are associated with sodium channel blockers much more frequently, such as lacosamide.

However, as a result of this question, I found this ...

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