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How soon after a fracture would it be safe to start anti-resorptive therapy?

3 Answers
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Rheumatology · U of AZ Phoenix Dept of Orthopaedics

This is an important question. There is no definitive answer, and there have been no clinical or preclinical studies that demonstrate delayed healing in the presence of bisphosphonates. Personally, I favor waiting a few weeks before we start. That also gives us time to do a proper metabolic workup. ...

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Geriatric Medicine · Harvard Medical School

Great question. We favor starting bisphosphonates, if patients are eligible, as soon as possible after a fragility fracture. Patients with recent fragility fractures often experience significant difficulty in achieving timely and regular outpatient follow-up, and IV bisphosphonates during the inpati...

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Rheumatology · Tidalhealth

Agree with Dr. @Dr. First Last. Inpatient is a great opportunity to infuse ZA into these patients, and they can be followed up as outpatients later on. However, most inpatient pharmacies do not carry ZA, and it is also debatable whether insurance will cover ZA infusion as an inpatient. So, though th...

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