In my experience, anastomotic strictures do not resolve spontaneously or with treatment interruptions. In part, the answer to this question depends on how symptomatic the patient is and how close you are to the end of treatment. If the patient is totally obstructed or close to it, you're probably go...

I agree with Dr. @Mitchell S. Anscher, and I'll back it up with some data. As we know from studies in other tumor types, there is a time lag for the development of radiation fibrosis. While at Duke, I led a small phase I trial of pre-operative prostate radiotherapy followed by prostatectomy (Koontz ...