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Topics:
Neurology • Journal Club ft. NEJM publications • Behavioral Neurology & Neuropsychiatry • Alzheimer's Disease
How will you counsel patients regarding ARIA?
Do you see utility in trending serum neurofilament light chain levels or any alternative screening methods beyond MRI to help identify amyloid-related imaging abnormalities earlier? How will you approach patients considering these treatments who cannot get MRIs?
Answer from: at Academic Institution
It is possible that with real-life experience and further study, blood biomarkers will be validated as early detection signs of ARIA, but right now we are left with MRI. I believe that we need a lot more real-world data about these drugs before we consider alternative ways to diagnose and screen for...
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Answer from: at Academic Institution
How will you counsel patients regarding ARIA?
I will convey the following: "ARIA is a side effect that does not usually cause any symptoms but serious symptoms can occur. ARIA is most commonly seen as temporary swelling in areas of the brain that usually resolves over time. Some people may also h...