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Topics:
Genitourinary Cancers
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Medical Oncology
•
Renal Cell Carcinoma
How will you manage a patient with refractory metastatic unclassified RCC with progression on IO/TKI?
How does unclassified histology inform your subsequent treatment consideration?
Related Questions
When, if ever, would you re-challenge with immunotherapy for patients with metastatic RCC?
If the patient has had prior partial nephrectomy for RCC, would you consider SBRT for a contralateral RCC?
Would you use adjuvant pembrolizumab for bilateral ccRCC with R1 resection?
What is your preferred approach to low volume unresectable/metastatic favorable risk RCC?
How would you approach the use of bevacizumab in metastatic FH-deficient RCC/HLRCC that is c/b extensive IVC tumor thrombus and DVT/PE?
In a patient with metastatic RCC who discontinued nivolumab after a prolonged response to ipilimumab/nivolumab, would you consider re-starting nivolumab at disease progression?
Would you offer adjuvant immunotherapy in a patient with high risk RCC with new/worsening post-op renal dysfunction and CrCl<30?
What is your treatment approach in localized RCC with VHL mutation after progression on belzutifan?
Would the occurrence of obvious tumor rupture/spillage intraoperatively impact your decision for adjuvant systemic therapy after resection of either clear cell RCC or papillary RCC?
How would you approach adjuvant systemic therapy for an isolated, oligometastatic CNS recurrence of RCC that was treated with SBRT?