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How would you approach a low to moderate titer of one of the APLS antibodies in a patient with a strong family history but no personal history of thrombosis?

Although testing was not indicated, what do u do with these results? Other hypercoagulability work up negative
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How would you approach APLS antibodies in a patient with family history but no personal history of thrombosis?

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2 Answers
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Rheumatology · UT Southwestern Medical Center
Answered on

I do not do anything as there are no data to support intervention in this case.

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Rheumatology · UTMB Health
Answered on

I would repeat these tests in about 12 weeks or so. Certain infections can transiently induce positive antiphospholipid antibodies, usually non-pathogenic, with certain exceptions.

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