How would you approach a patient with well controlled metastatic lung cancer who develops a new primary P16 positive oropharyngeal squamous cell carcinoma?
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3 Answers
Mednet Member
Medical Oncology · Donald and Barbara Zucker School of Medicine at Hofstra/Northwell
Multiple primaries are not uncommon. Given tremendous advances in treatments of advanced lung cancer and consequent improvement in overall survival, it is important to focus on screening, early detection, and curative-intent of other cancers whenever applicable. This seems to be one such situation.
...Mednet Member
Medical Oncology · University of Michigan Medical School
Treatment of this patient's p16+ oropharynx primary would depend on a few factors. One, how well is this patient's lung cancer controlled? Moreover, if the cancer has a prolonged PF interval due to a response induced by a checkpoint inhibitor or perhaps a RET targeted therapy? If so, then I may cons...