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How would you approach a small mucinous adenocarcinoma of the anal verge (without anal canal involvement) with positive margins after resection?

Further surgery is not possible.
2 Answers
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Radiation Oncology · Varian Medical Systems/Allegheny health network
Answered on

If resection is not feasible to get negative margins without an APR then I would favor treating with concurrent chemo (xeloda) with RT to a dose in mods 50s to area of positive margin.

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Radiation Oncology · University of Texas MD Anderson Cancer Center
Answered on

Agree with concurrent (xeloda-based) chemoradiation 50-54Gy and close observation subsequently.

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