How would you approach adjuvant therapy for a finding of carcinosarcoma in a prostatectomy specimen?

Pure "carcinosarcoma" a biphasic neoplasm with both epithelial adenocarcinoma with second component which is a clearly recognizable type of sarcoma is of course extremely rare, thus my comments must be considered in the data free zone from which they eminate. Both local recurrence and systemic failu...

Good surgical resection is the mainstay of treatment and whether an extended lymph node dissection is further needed has not been well studied for these rare variant. No chemotherpay is indicated post-operatively but close observation with serial imaging since many of these will be non-PSA secreting...