How would you approach adjuvant therapy for a fully resected vulvar carcinoma with a single positive lymph node?
Margins widely negative - 1cm, and full bilateral inguinofemoral lymphadenectomy performed.
Answer from: at Community Practice
There is not a simple answer to this question. In most cases, omitting adjuvant therapy is appropriate, but in certain cases, adjuvant radiation therapy + chemotherapy is advised, even in the presence of only a single positive lymph node. It has been over 30 years since Homesley and co-workers&rsquo...
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Answer from: at Academic Institution
Data, now 30-40 yrs old, noted that patients with only one positive node had a survival comparable to those with negative nodes.