How would you approach adjuvant therapy for a fully resected vulvar carcinoma with a single positive lymph node?
Margins widely negative - 1cm, and full bilateral inguinofemoral lymphadenectomy performed.
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What is your preferred adjuvant regimen for fully resected, T1 SCC of the vulva with single positive groin node (>5mm, no extension)?
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2 Answers
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Gynecologic Oncology · Center of Hope
Answered on
There is not a simple answer to this question. In most cases, omitting adjuvant therapy is appropriate, but in certain cases, adjuvant radiation therapy + chemotherapy is advised, even in the presence of only a single positive lymph node. It has been over 30 years since Homesley and co-workers’ 1986...
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Mednet MemberInvited Expert
Gynecologic Oncology · Medical University of South Carolina
Answered on
Data, now 30-40 yrs old, noted that patients with only one positive node had a survival comparable to those with negative nodes.
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