How would you approach endoscopic diagnosis and treatment of an area of visible nodularity concerning for cancer within long segment Barrett’s esophagus?  

I would begin by careful inspection of the Barrett's (BE) mucosa under HD-white light and narrow band imaging after washing off the surface mucus. I would evaluate the entire BE segment for nodules, ulcers, irregularities in pit-pattern and focal changes in vascular pattern, raising suspicion for in...