How would you approach ES-SCLC presenting with small brain metastases that resolve after chemotherapy?
No prior brain radiation. Is full dose whole brain radiation mandated? Would you consider PCI dose or brain surveillance?
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How would you approach ES-SCLC presenting with small brain metastases that resolve after chemotherapy?
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3 Answers
Mednet MemberInvited Expert
Radiation Oncology · Quillen VA Medical Center
Answered on
ES-SCLC may respond to chemotherapy, but save for a select few, it’s a palliative disease with, median survival of about a year for responders. Presenting with microscopic brain disease that responds to chemo does not change that. The Slotman report indicating survival advantage has been questioned ...
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Radiation Oncology · UC San Diego School of Medicine
Answered on
Brain mets that resolve with chemo... Follow with surveillance MRI q3 months and treat at progression with SRS preferably or WBRT if necessary. This is not really a PCI question as they have known mets.
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Radiation Oncology · University of Florida
Answered on
MR in 3 months.
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