How would you approach ES-SCLC presenting with small brain metastases that resolve after chemotherapy?

Topics: Radiation Oncology • Thoracic Malignancies

No prior brain radiation. Is full dose whole brain radiation mandated? Would you consider PCI dose or brain surveillance?

Answer from: Radiation Oncologist at Community Practice

ES-SCLC may respond to chemotherapy, but save for a select few, it’s a palliative disease with, median survival of about a year for responders. Presenting with microscopic brain disease that responds to chemo does not change that. The Slotman report indicating survival advantage has been quest...

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Radiation Oncologist at West Virginia University
I generally agree with Dr. @Andrew T. Turrisi but ...

Answer from: Radiation Oncologist at Academic Institution

Brain mets that resolve with chemo... Follow with surveillance MRI q3 months and treat at progression with SRS preferably or WBRT if necessary. This is not really a PCI question as they have known mets.

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Radiation Oncologist at Marshall University - Edwards Comprehensive Cancer Center
Have a similar case - a single asymptomatic 6 mm b...

Radiation Oncologist at Physician Health Partners
Need randomized study for definite answers.

Answer from: Radiation Oncologist at Academic Institution

MR in 3 months.

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