How would you approach management of a patient with checkpoint inhibitor induced psoriatic arthritis?
Pt with active skin and joint disease. Previously on Cemiplimab (PD-1) for squamous cell carcinoma of the skin. Do you avoid traditional DMARDs due to increased skin cancer risk?
1 Answer
Mednet MemberInvited Expert
Rheumatology · Johns Hopkins School of Medicine
Answered on
We will often try a short course of steroids if this is new psoriatic arthritis due to immune checkpoint inhibitor therapy. We then consider a DMARD like methotrexate or biologic. If biologics are needed, we will typically choose an IL-12/23 or IL-23 inhibitor or a TNF inhibitor.
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