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How would you approach management of a recurrent, high grade stromal sarcoma (ovarian origin) with progression on doxorubicin?  

Stage IVB at diagnosis, ovarian primary arising in background of endometriosis. Initially responded to carbo/taxol/avastin, however recurred 2 months after discontinuation and progressed through doxorubicin.

ER/PR negative, no actionable mutations on germline/somatic tumor testing.