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How would you approach patient selection for DBS after chronic post-stroke for motor rehabilitation in light of the recent phase 1 clinical trial?

Baker KB, Plow EB, Nagel S, et al. Cerebellar deep brain stimulation for chronic post-stroke motor rehabilitation: a phase I trial. Nat Med. 2023;29:2366-2374. doi:10.1038/s41591-023-02507-0
1 Answer
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Neurosurgery · University of Arizona
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These two neurostimulation modalities occupy fundamentally different positions in the treatment landscape. VNS paired with rehabilitation (Vivistim) is the only FDA-approved neuromodulation therapy for chronic post-stroke upper-extremity motor rehabilitation, supported by a pivotal phase III RCT and...

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