How would you approach patients with resected, node positive (N1/N2) Large Cell Neuroendocrine Carcinoma of the Lung who have ESRD on dialysis?

This is certainly a challenging situation, both because of the relative scarcity of data for LCNEC in general as well as the limitations placed in patients with organ dysfunction including requirement of HD.

First issue is the question of adjuvant treatment for LCNEC. The role of adjuvant chemotherap...