Mednet Logo
HomeNeurologyQuestion

How would you approach the treatment of checkpoint-inhibitor-mediated temporal arteritis?

1
2 Answers
Mednet Member
Mednet Member
Rheumatology · Johns Hopkins School of Medicine

Temporal arteritis or GCA is a rare immune related adverse event due to immune checkpoint inhibitor (ICI) therapy. Corticosteroids are the first line treatment, along with holding the ICI. As there have been limited cases, there is not evidence for IVIG in this setting.

Register or Sign In to see full answer

Mednet Member
Mednet Member
Rheumatology · Washington University Physicians

I agree; isolated cases with significant glucocorticoid adverse effects or evidence of additional large vessel involvement may require the addition of tocilizumab to obtain control of their disease.

Register or Sign In to see full answer