How would you approach therapy in a young adult with synovial sarcoma of the head and neck who is not amenable to surgery due to location on the face?
Answer from: Medical Oncologist at Academic Institution
I do not think primary synovial sarcoma is curable without surgery. I have never seen a durable response in a tumor treated with radiation alone. Synovial sarcoma responds to ifosfamide based chemotherapy generally, but in my experience, the response rates for primary tumors are lower than response ...
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Answer from: Radiation Oncologist at Academic Institution
Unlikely to cure without surgery. GTR and postop RT. If not suitable for GTR, RT and prayer.