How would you approach unexpected chemo breaks during planned neoadjuvant chemoradiation for esophageal adenocarcinoma?

How would you approach unexpected chemo breaks during planned neoadjuvant chemoradiation for esophageal adenocarcinoma?

• Continue RT, proceed with surgery as planned
• Continue RT, sequential chemo if patient tolerates, then proceed with surgery
• Continue RT, proceed with surgery with planned, then adjuvant chemo
• Hold RT, proceed to surgery
• Hold RT until patient can tolerate resuming chemoradiation within a reasonable timeframe, then surgery
• Other