How would you define bulky involvement of the tonsil in a patient with DLBCL?

Topics: Hematologic Malignancies • Radiation Oncology

The patient in question has Stage IIIA DLBCL with a CR after 6 cycles R-CHOP. When would you treat the involved tonsil?

Answer from: Radiation Oncologist at Academic Institution

While the definition of "bulky" disease has been relatively consistent in the Hodgkin literature, the definition in prospective DLBCL trials has not. For example... ECOG 1484 - 10 cm SWOG 8736 & SWOG 0014 - 10 cm GELA 93-1 & 93-4 - 10 cm RICOVER-60 & RICOVER-noRTh - 7.5 cm UNFOLDER ...

Comments

Radiation Oncologist at Toledo Clinic Inc.
Thank you, very detailed and helpful.

Related Questions