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How would you escalate treatment for a pediatric patient with CNO with mandibular involvement and only partial response to biweekly TNFi?

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How would you escalate treatment for a pediatric patient with CNO with mandibular involvement and only partial response to biweekly TNFi?

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1 Answer
Mednet Member
Mednet MemberInvited Expert
Rheumatology · University of Alabama Birmingham
Answered on

If you are convinced of the correct diagnosis, then adding pamidronate to TNFi would be my suggestion. Additionally, you could maximize TNFi dose/interval (e.g., adalimumab 40 mg weekly).

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