How would you manage a CML patient with a T315I mutation that developed severe abdominal pain requiring hospitalization after starting ponatinib 45 mg?

If abdominal pain started after ponatinib was started it is important to rule out complications related to the drug. Thrombosis was ruled out, which is important as ponatinib can cause venous and arterial thrombosis. It is also important to rule out pancreatitis. If no other etiology is found and th...