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How would you manage a Grade II IDH mutant astrocytoma with otherwise low risk features, but gemistocytic histology?

Do you treat this as a higher grade tumor or alter your adjuvant recommendations?
1 Answer
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Radiation Oncology · Columbia University Irving Medical Center
Answered on

Not sure there is a right answer for this one - in general, for an IDH mutant grade 2 astrocytoma with low risk features, I would consider observation. If all else is low risk with the exception of gemistocytic histology, I may still consider observation and counsel the patient about an increased ri...

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