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How would you manage a new suspected brain metastasis in a patient with a distant cancer history?

Would you consider empiric SRS if biopsy/resection is not feasible? When would you consider liquid biopsy?
2 Answers
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Radiation Oncology · Columbia University Irving Medical Center
Answered on

So I think there are some details missing but generally, if there is a suspected brain metastases in a patient with distance cancer history and that biopsy/resection is not feasible, I would consider additional workup including extracranial imaging. If the suspected brain metastases is asymptomatic ...

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Radiation Oncology · University of Missouri at Columbia, Ellis Fischel Cancer Cener
Answered on

I agree, there are assumptions here. Not certain why surgery or biopsy is not feasible. And just for the record, there is some uncertainty of whether this is a metastasis, vs primary brain malignancy or infection. 10% of patients in the original Patchell trial were ineligible because their lesions p...

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