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Topics:
Hematologic Malignancies
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Medical Oncology
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Leukemia
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CML
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Hematology
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Cardiology
How would you manage a patient with CML in chronic phase with a significant cardiac history, such as heart failure with reduced ejection fraction or arrhythmia?
Is there a specific tyrosine kinase inhibitor that you would prefer to use?
Related Questions
How would you treat a patient with chronic phase CML who could not tolerate nilotinib due to G4 thrombocytopenia despite sequential dose reductions?
How do you approach a patient with CP-CML who has a history of inadequate response and severe myelotoxicity to multiple TKIs such as imatinib, nilotinib and dasatinib?
Do you switch from imatinib to another TKI in patients with chronic phase CML who develop renal insufficiency?
Based on the ASC4MORE trial, would you add asciminib to imatinib if patients don’t achieve deep molecular remission at 1 year?
What is your current approach to maintenance therapy in FLT3-mutant AML post allogeneic HCT?
How do you treat a patient with chronic phase CML who developed severe prolonged thrombocytopenia with reduced dose nilotinib and then imatinib?
What's the role of ibrutinib and venetoclax in CLL in light of data emerging from ASH 2022?
Do you prefer quizartinib over midostaurin with chemotherapy induction for FLT3-ITD mutated AML given the results of QUANTUM-FIRST and preclinical advantages over other FLT3 inhibitors?
Would you use a matched sibling donor with a germline heterozygous BRCA1 mutation for stem cell transplant?
Would you consider TKI discontinuation in a patient who has negative BCR transcripts on Bosutinib?