How would you manage a patient with history of locally advanced SCC of the cervix, treated with definitive chemoRT, found to have new lung lesions 6 months post treatment?

All patients with metastatic cervical cancer should first be considered for a clinical trial. This is a condition with limited effective treatment options and also disproportionately affects younger women. It is pivotal clinicians be aware of the rapidly evolving landscape of clinical therapies for these patients. Several therapeutic options for patients with metastatic cervical cancer are currently being evaluated for accelerated FDA approval and will likely be available for clinical use in the...

If clinical and functional status allows it, I would treat with carbo/taxol/bev and consider maintenance Bev.

In the meantime, I would ask for PDL-1 tumor testing for possible immunotherapy.