How would you manage a patient with newly diagnosed locally advanced NSCLC and concurrent, active tuberculosis on anti-TB therapy?
After initiation of anti-TB treatment and 3 negative AFB smears, would you initiate concurrent chemoRT? Would you give sequential RT then chemo to give patient more time on the anti-TB treatment before adding immunosuppressive chemotherapy?
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How would you manage a patient with locally advanced NSCLC and active tuberculosis on anti-TB therapy?
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Medical Oncology · UCLA
Answered on
Excellent question @Dr. First Last!
Assuming the patient is otherwise a good candidate for concurrent chemoRT, my bias would be to proceed with concurrent therapy once the 3 negative AFBs are available, rather than pursue sequential RT then chemo.
This recommendation is based upon the observation th...
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