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How would you manage a patient with recurrent stage IIIC granulosa tumor following secondary, R0 cytoreduction?

Primary R0 debulking in 2018 followed by Carbo/Tax for 6 cycles, and single agent Bevacizumab followed by Letrozole, now again with NGR
1 Answer
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Gynecologic Oncology · Cooper Medical School of Rowan University
Answered on

There is not a lot of data to go on in this situation. R0 resection is probably one of the best predictors for survival. Karalok et al., PMID 27174627 reported on a series of 18 patients undergoing resection of recurrent disease. Complete resection resulted in PFS and OS > 200 months.

In general, the...

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