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How would you manage a solitary unresectable liver metastasis?

From NCCN (Rectal MS-33): SBRT is a reasonable option for patients who cannot be resected or ablated. What is the role of SBRT versus microwave ablation?
2 Answers
Mednet Member
Mednet Member
Radiation Oncology · West Virginia University Medicine
Answered on

Excellent question!

Before starting any systemic treatments, has the patient undergone an MRI? Conducting an MRI prior to systemic therapy is crucial for accurately determining whether there are single or multiple liver metastases. The CAMINO study has shown that incorporating an MRI at the initial ...

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Mednet Member
Mednet Member
Radiation Oncology · University of Illinois, College of Medicine
Answered on

In general, the local treatment options for unresectable solitary liver metastasis are:

  1. External beam with photon (SBRT/IMRT/3-D)
  2. Trans-Arterial Radio-Embolization (TARE) with Yttrium-90 microspheres
  3. Proton beam therapy
  4. Interventional ablation

The optimal treatment depends on the tumor size, locati...

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