How would you manage a T2N0 anal squamous cell carcinoma in a patient with a history of FAP s/p remote proctocolectomy with J pouch creation?

Topics: Radiation Oncology • Gastrointestinal Cancers

Would you offer standard ChemoRT or favour APR given the risks associated with RT?

Answer from: Radiation Oncologist at Community Practice

This is a rare situation. The more common would be an adenocarcinoma developing in residual rectal mucosa after proctocolectomy for ulcerative colitis or FAP. If disease is locally advanced in those cases, and therefore an indication for radiotherapy, I’ve favored pre-op total neoadjuvant ther...

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Radiation Oncologist at Washington University School of Medicine
The main consideration here is potential chronic p...

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