Topics:
Head and Neck Cancers • Radiation Oncology
How would you manage locally advanced head and neck patients getting definitive chemoradiation who show progression halfway through treatment?
Do you alter treatment and/or fractionation?
Answer from: Radiation Oncologist at Community Practice
I have seen this twice within the last year. Here is what we did:
1) First patient had high risk cutaneous SCC s/p WLE and neck dissection. He progressed in the skin after surgery when seen for sim, and continued to progress during first week of RT. We stopped RT, started cemiplimab. He had a remar...
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Answer from: Radiation Oncologist at Academic Institution
This is a very unusual event. Make sure it’s real. Step on the gas and accelerate/hyperfractionate.