How would you manage new onset amenorrhea, diabetes insipidus and growth hormone deficiency without other pituitary deficiencies or excess in young females with MRI findings of pituitary mass and hypothalamic edema?  

Impossible to say without seeing the images. I would however image her chest in search of sarcoidosis and obtain a skeletal survey as 2/3 of patients with LCH have bone lytic lesion. Would also consider LP to measure germ cell tumor markers and to search for possible evidence of lymphoma. DI is most...