How would you manage RT for a locally advanced squamous cell carcinoma of the anal canal in a >90-year old if chemotherapy is not recommended?
Would you go to a higher dose for the primary and/or nodal volumes?
If the medical oncologist does not feel comfortable giving cisplatin or mitomycin C, would you push for single agent 5-FU concurrent with RT, or just give RT alone?
2 Answers
Mednet MemberInvited Expert
Radiation Oncology · UT Southwestern Medical Center
Answered on
For any elderly patient, a discussion of goals of care in the context of symptoms is warranted. In the chance this is a small asymptomatic cancer in a patient with limited life expectancy, no therapy may be reasonable. However, this does not seem to be the case for your patient.
If the patient is deemed a poor candidate for MMC/cisplatin, I would discuss concurrent 5-FU (perhaps low dose) or capecitabine with the medical oncology team. There are several published series on this, and I believe tha...
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Mednet MemberInvited Expert
Radiation Oncology · University of Florida
Answered on
RT alone.
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