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How would you manage RT for a locally advanced squamous cell carcinoma of the anal canal in a >90-year old if chemotherapy is not recommended?

Would you go to a higher dose for the primary and/or nodal volumes? If the medical oncologist does not feel comfortable giving cisplatin or mitomycin C, would you push for single agent 5-FU concurrent with RT, or just give RT alone?
2 Answers
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Radiation Oncology · UT Southwestern Medical Center
Answered on

For any elderly patient, a discussion of goals of care in the context of symptoms is warranted. In the chance this is a small asymptomatic cancer in a patient with limited life expectancy, no therapy may be reasonable. However, this does not seem to be the case for your patient.

If the patient is dee...

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Mednet Member
Mednet MemberInvited Expert
Radiation Oncology · University of Florida
Answered on

RT alone.

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