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How would you manage tubulointerstitial nephritis and renal tubular acidosis (RTA) in a patient with Sjogren's who is pregnant?

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Mednet Member
Mednet Member
Rheumatology · NYU Long Island School of Medicine

The most common form or renal disease in Sjogren's (SjD) is tubulointerstitial nephritis. This may result in tubular dysfunction leading to renal tubular acidosis (RTA), most commonly type I RTA leading to hypokalemia and a non-anion gap hyperchloremic acidosis. Over time, nephrocalcinosis can occur...

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Mednet Member
Mednet Member
Nephrology · Ohio State Department Of Nephrology

I have seen quite a few RTAs in my obstetric nephrology fellowship. Potassium citrate requirements tend to increase throughout pregnancy so will need frequent assessment and adjustment.

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