How would you mange true anal margin squamous cell carcinoma (with no involvement of anal canal) if wide local excision cannot be done and chemoradiation therapy is being used instead?  

Anal cancer guidelines mostly refer to anal canal tumors with less information about tumors of skin in perianal area (ie true anal margin).

Would IMRT be appropriate?

What nodal targets would you treat? Would you treat peri-rectal nodes and uninvolved anus/rectal areas?



Answer from: Radiation Oncologist at Academic Institution
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Radiation Oncologist at Providence St Mary Cancer Center
Thanks for your answer. I'm probably missing somet...
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Answer from: Radiation Oncologist at Academic Institution