How would you modify adjuvant radiation for oral cavity SCC based on the presence of sarcomatoid features?
Answer from: Radiation Oncologist at Academic Institution
Suggest to discuss the sarcomatoid features with the pathologist. There are two possibilities:1. Spindle cell carcinoma is a variant of squamous cell carcinoma characterized by spindled or pleomorphic cells that appear to be sarcoma but are actually epithelial. Some of these can be HPV-related and h...
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Answer from: Radiation Oncologist at Academic Institution
I treat as I would a poorly differentiated SCC.