How would you optimally manage a small solitary plasmacytoma of the alveolar ridge, including minimizing the risk of dental toxicity?

The alveolar ridge is an osseous structure (extension of the mandible and maxilla) that houses the sockets of the teeth. Assuming an appropriate work-up demonstrates no evidence of multiple myeloma (bone marrow biopsy, PET-CT/MRI, laboratory work, etc.), a plasmacytoma arising in this region would be classed as a solitary plasmacytoma of bone.

Solitary plasmacytomas (osseous and extramedullary) are relatively rare and there are limited studies evaluating the optimal management. After definitive ...