How would you palliate a metastatic lesion abutting a joint with an associated effusion?

I don't know that there is data for this - not that I could find.

Bone metastases themselves cause pain due to multiple factors - mass effect, inflammation, and microenvironment changes. I'd guess the effusion is potentially due to the existence of the metastases (an inflammatory reaction), rather t...

I have never worried about this, but the closest similar scenario would be a pleural metastasis with a malignant pleural effusion. You treat the cancer that is causing the symptom (which is the pleural met that is say, invading the rib, or spine, or chest wall, or lung or bronchial tree, etc.) and n...