How would you treat a metastatic pancreatic cancer patient who develops symptomatic leptomeningeal disease on first line FOLFIRINOX?

Topics: Gastrointestinal Cancers • Medical Oncology • Liver and Pancreas Tumors • NCI-CCC Tumor Board Question • Indiana University • NCI-CCC GI Tumor Board Question

Answer from: Medical Oncologist at Academic Institution

This is a really unfortunate situation. There is some evidence that gemcitabine, at least, crosses the blood-brain barrier and there is at least one case report of a patient in a similar situation responding to gemcitabine/nab-paclitaxel. Given this and the paucity of data supporting other options f...

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Medical Oncologist at McLeod Regional Medical Center at McLeod Seacoast
I think you can safely say that there is no eviden...

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