How would you treat a metastatic small cell carcinoma of the larynx that is locally progressing on cisplatin/etoposide?

What dose and fractionation would you use, and would it differ from other types of H&N cancers?

Would you consider Quadshot scheme?

Answer from: Radiation Oncologist at Academic Institution

I assume metastatic means distantly metastatic. 30 Gy/10 fx or 20 Gy/5 fx local regional RT if progressing on chemo.

Comments

Radiation Oncologist at Memorial Sloan Kettering Cancer Center
Or we can consider Quad Shot. A randomized study f...

Radiation Oncologist at UPMC Hillman Cancer Center
@Sushil Beriwal-

Radiation Oncologist at University of Florida
It would not differ.